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Impaired wound healing is one of the major complications of diabetes, involving prolonged inflammation, delayed re-epithelialization, and consistent oxidative stress. The detailed mechanism remains unclear, and there is currently no effective treatment for diabetic wound healing. In this study, we aim to investigate the potential role and effect of nuclear factor erythroid-2—related factor-2 Nrf2 activation on diabetic wound healing. Both Nrf2 overexpression and Nrf2 activator dimethyl fumarate DMF treatment ificantly ameliorated oxidative stress and inflammation.

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This is an ongoing project and we frequently search the following databases for pediatric studies: Medline, Embase and the Cochrane Central Registry of Trials. The table can be browsed by conditions or searched by using Evergreen Fall River massage, author names, journal names, publication year, or treatments.

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